Felix C Tanner Selected Research

Thromboplastin (Tissue Factor)

10/2020	Murine tissue factor disulfide mutation causes a bleeding phenotype with sex specific organ pathology and lethality.
1/2018	Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity.
1/2017	The MAP kinase JNK2 mediates cigarette smoke-induced arterial thrombosis.
1/2017	Tissue Factor Expression Does Not Predict Mortality in Breast Cancer Patients.
9/2014	Epigenetic regulation of tissue factor inducibility in endothelial cell senescence.
10/2013	p27(Kip1) inhibits tissue factor expression.
5/2012	Caffeine induces endothelial tissue factor expression via phosphatidylinositol 3-kinase inhibition.
8/2011	Dietary α-linolenic acid inhibits arterial thrombus formation, tissue factor expression, and platelet activation.
2/2011	Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells.
7/2010	Amphetamines induce tissue factor and impair tissue factor pathway inhibitor: role of dopamine receptor type 4.

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Felix C Tanner Research Topics

Disease

31	Thrombosis (Thrombus) 06/2020 - 03/2005
11	Atherosclerosis 11/2014 - 04/2005
9	Cardiovascular Diseases (Cardiovascular Disease) 04/2021 - 11/2003
7	Heart Failure 01/2022 - 01/2012
7	Aortic Valve Stenosis (Aortic Stenosis) 10/2020 - 08/2011
6	Inflammation (Inflammations) 10/2021 - 05/2010
6	Acute Coronary Syndrome 11/2012 - 07/2005
5	Myocardial Infarction 01/2022 - 03/2005
5	Neoplasms (Cancer) 01/2018 - 01/2006
3	Mitral Valve Insufficiency (Mitral Regurgitation) 01/2020 - 03/2016
3	Cardiomyopathies (Cardiomyopathy) 01/2019 - 01/2012
3	Aortic Valve Insufficiency (Aortic Regurgitation) 10/2016 - 03/2013
3	Hypertension (High Blood Pressure) 08/2014 - 11/2003
3	Death (Near-Death Experience) 03/2014 - 05/2013
3	Vascular Diseases (Vascular Disease) 11/2011 - 01/2006
2	Arrhythmogenic Right Ventricular Dysplasia (Arrhythmogenic Right Ventricular Cardiomyopathy) 01/2022 - 01/2012
2	Heart Diseases (Heart Disease) 01/2022 - 01/2018
2	COVID-19 10/2021 - 12/2020
2	Infections 10/2021 - 10/2015
2	Pericarditis 10/2021 - 05/2013
2	Pathologic Constriction (Stenosis) 06/2020 - 09/2014
2	Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve) 04/2019 - 02/2017
2	Obesity 01/2019 - 02/2011
2	Arterial Occlusive Diseases (Arterial Occlusive Disease) 01/2018 - 01/2017
2	Coronary Thrombosis 01/2018 - 02/2007
2	Stroke (Strokes) 01/2018 - 08/2014
2	Pulmonary Hypertension 10/2017 - 03/2015
2	Chronic Renal Insufficiency 10/2016 - 11/2014
2	Ventricular Tachycardia 06/2015 - 03/2014
2	Hyperglycemia 08/2014 - 03/2007
2	Syncope (Fainting) 03/2014 - 01/2012
2	Necrosis 05/2012 - 07/2010
2	Atrial Fibrillation 12/2009 - 02/2008
1	Bicuspid Aortic Valve Disease 10/2022
1	Myocarditis (Carditis) 10/2021
1	Chest Pain (Chest Pains) 10/2021
1	Granuloma 01/2021
1	Hemorrhage 10/2020
1	ST Elevation Myocardial Infarction 01/2018
1	Carotid Artery Thrombosis 01/2018
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Fibrosis (Cirrhosis) 01/2016
1	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2016
1	Diverticulum 06/2015

Drug/Important Bio-Agent (IBA)

23	Thromboplastin (Tissue Factor)IBA 10/2020 - 04/2005
8	Proteins (Proteins, Gene)FDA Link 09/2014 - 04/2005
4	oxidized low density lipoproteinIBA 10/2016 - 05/2010
4	lipoprotein-associated coagulation inhibitor (TFPI)IBA 11/2014 - 05/2006
4	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2011 - 03/2007
4	MetalsIBA 01/2010 - 02/2007
3	Thrombin FDA Link 09/2014 - 07/2010
3	PolymersIBA 01/2008 - 02/2007
3	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2006 - 11/2003
2	pro-brain natriuretic peptide (1-76)IBA 01/2022 - 06/2017
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2022 - 01/2022
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2021
2	Troponin T (Troponin T1)IBA 10/2021 - 01/2016
2	LipidsIBA 04/2021 - 01/2019
2	LDL Lipoproteins (beta Lipoproteins)IBA 10/2016 - 11/2014
2	Apolipoproteins E (ApoE)IBA 10/2014 - 01/2011
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2014 - 07/2007
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2014 - 07/2010
2	Sirtuin 1IBA 02/2011 - 06/2010
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 01/2010 - 10/2006
2	Interleukin-6 (Interleukin 6)IBA 04/2008 - 03/2005
2	Celecoxib (Celebrex)FDA Link 10/2006 - 11/2003
1	GadoliniumIBA 01/2022
1	Growth Differentiation Factor 15IBA 01/2022
1	VaccinesIBA 10/2021
1	Messenger RNA (mRNA)IBA 10/2021
1	mRNA VaccinesIBA 10/2021
1	Natriuretic PeptidesIBA 10/2021
1	Neuroprotective AgentsIBA 04/2021
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 04/2021
1	SteroidsIBA 01/2021
1	DisulfidesIBA 10/2020
1	Triglycerides (Triacylglycerol)IBA 01/2019
1	LipopolysaccharidesIBA 01/2018
1	SirtuinsIBA 01/2018
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2018
1	Sirtuin 3IBA 01/2018
1	NAD (NADH)IBA 01/2018
1	Contrast MediaIBA 02/2017
1	Phosphotransferases (Kinase)IBA 01/2017
1	SmokeIBA 01/2017

Therapy/Procedure

10	Therapeutics 01/2022 - 02/2009
9	Stents 03/2014 - 07/2006
8	Transcatheter Aortic Valve Replacement 10/2022 - 08/2011
7	Drug-Eluting Stents 03/2014 - 07/2006
4	Prostheses and Implants (Prosthesis) 06/2020 - 08/2011
3	Heart Transplantation (Grafting, Heart) 03/2014 - 05/2013
2	Lasers (Laser) 01/2018 - 11/2014
1	Minimally Invasive Surgical Procedures 01/2021
1	Aftercare (After-Treatment) 01/2020
1	Catheters 01/2018
1	CT protocol 02/2017
1	Intravenous Administration 10/2016
1	Mitral Valve Annuloplasty 10/2016
1	Heart-Lung Machine 10/2015
1	Catheter Ablation 06/2015